| 建系背景 |
established from the peripheral blood of a 20-year-old ma n with acute myeloid leukemia AML FAB M5a at relaps e in 1995 after initial myelodysplastic syndrome (MDS, ref ractory anemia with excess of blasts, RAEB); described to carry internal tandem duplication of FLT3; the FLT3 pr otein is not expressed; cell line carries the CBL deltaExo n8 mutant; sister cell line of MOLM-14 (ACC 777). Ex ome and RNA sequence data are available (see Ref 1818 7 and Exome sequence and RNA-Seq)。 |
